Article

Global expression profile of Enterohemorrhagic <i>Escherichia coli</i> O157:H7 in phagosome of murine macrophages

2025-01-04

Abstract excerpt

EHEC O157:H7 is responsible for Hemolytic Uremic Syndrome (HUS) outbreaks in humans and its virulence is associated with Shiga toxin (Stx). During the pathogenesis of HUS, EHEC O157:H7 is phagocytized by the intestinal host macrophage into the phagosome. According to our study, a low percentage of phagocytized bacteria survived in the murine macrophage phagosome. To understand the initials mechanisms involved in b...

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Literature Corpus work: 3d1ecba7-d498-5599-b97f-4c5d26788093
DOI: 10.1101/2024.12.18.629128

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