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Pathogenicity, Host Responses and Implications for Management of Enterohemorrhagic<i>Escherichia coli</i>O157:H7 Infection

1 Jan 2013

Abstract excerpt

Enterohemorrhagic Escherichia coli serotype O157:H7 is a food- and waterborne pathogen that causes significant morbidity and mortality in both developing and industrialized nations. The present review focuses on the history, epidemiology and evolution of the pathogen; provides a mechanistic overview of major virulence factors (including Shiga toxins, locus of enterocyte effacement pathogenicity island and pO157...

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PMID: 23712303
DOI: 10.1155/2013/138673

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