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Escherichia coliO157:H7 Survives within Human Macrophages: Global Gene Expression Profile and Involvement of the Shiga Toxins

26 Aug 2008

Abstract excerpt

Escherichia coli O157:H7 is an important food-borne pathogen that specifically binds to the follicle-associated epithelium in the intestine, which rapidly brings this bacterial pathogen in contact with underlying human macrophages. Very little information is available about the interaction between E. coli O157:H7 and human macrophages. We evaluated the uptake and survival of strain EDL933 during infection of...

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PMID: 18725421
DOI: 10.1128/iai.00446-08

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