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Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survival

2023-04-07

Abstract excerpt

<h4>ABSTRACT</h4> The plasma cell cancer multiple myeloma (MM) varies significantly in genomic characteristics, response to therapy, and long-term prognosis. To investigate global interactions in MM, we combined a known protein interaction network with a large clinically annotated MM dataset. We hypothesized that an unbiased network analysis method based on large-scale similarities in gene expression, copy number...

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Literature Corpus work
3cbb7b2a-6172-5c78-bd89-9ad72771abb7
DOI
10.1101/2023.04.05.535155
Open publication

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Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survivalDOI 10.1101/2023.04.05.535155
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