DNA damage repair (DDR) related prognostic risk model in multiple myeloma based on single-cell and bulk sequencing.

Abstract excerpt

Genomic rearrangements and instability are key pathological features of multiple myeloma (MM). However, the origins of DNA damage in MM and its impact on disease progression remain incompletely understood. Here, we screened DNA damage repair (DDR) genes from single-cell RNA sequencing and bulkRNA-seq datasets using WGCNA and differential expression analysis. A prognostic model was constructed, demonstrating that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA Damage
• Share to DNA Repair
• Share to Gene Expression Regulation, Neoplastic