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HCMV miRNA Targets Reveal Important Cellular Pathways for Viral Replication, Latency, and Reactivation

22 Oct 2018

Abstract excerpt

It is now well appreciated that microRNAs (miRNAs) play a critical role in the lifecycles of many herpes viruses. The human cytomegalovirus (HCMV) replication cycle varies significantly depending on the cell type infected, with lytic replication occurring in fully-differentiated cells such as fibroblasts, endothelial cells, or macrophages, and latent infection occurring in less-differentiated CD14+ monocytes and...

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PMID: 30360396
DOI: 10.3390/ncrna4040029

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