Article

Sir2 non-autonomously controls differentiation of germline cells in the ovary of <i>Drosophila melanogaster</i>

2019-05-08

Abstract excerpt

In Drosophila ovary, germline stem cells (GSCs) reside in a somatic cell niche that provides them signals necessary for their survival and development. Escort cells (ECs), one of the constituents of the niche, help in differentiation of GSC daughter cells. Since nutritional state is known to affect oogenesis, we set out to address the role of a metabolic sensor. NAD-dependent Sir2 is known to acts as a regulator...

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Literature Corpus work: 3ca70ce7-1cd2-54fd-b322-c0ec8401359c
DOI: 10.1101/631176

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