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Article

Identification and validation of tumor environment phenotypes in lung adenocarcinoma by integrative genome-scale analysis.

Cancer immunology, immunotherapy : CII - 1 Jul 2020

Bi Guoshu, Chen Zhencong, Yang Xiaodong, Liang Jiaqi, Hu Zhengyang, Bian Yunyi, Sui Qihai, Li Runmei, Zhan Cheng, Fan Hong

Abstract excerpt

PURPOSE: To comprehensively elucidate the landscape of the tumor environment (TME) of lung adenocarcinoma (LUAD), which has a profound impact on prognosis and response to immunotherapy. METHODS AND MATERIALS: Using a large dataset of LUAD patients from The Cancer Genome Atlas, Gene Expression Omnibus database (GEO), and our institution (n = 1411), we estimated the infiltration pattern of 24 immune cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32189030
DOI: 10.1007/s00262-020-02546-3
PMCID: PMC11027644

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