Article

Meta-analysis of preclinical pharmacogenomic studies to discover robust and translatable biomarkers of drug response

2022-10-24

Abstract excerpt

Preclinical pharmacogenomic studies provide an opportunity to discover novel biomarkers for drug response. However, pharamcogenomic studies linking gene expression profiles to drug response do not always agree on the significance or strength of biomarkers. We apply a statistical meta-analysis approach to 7 large independent pharmacogenomic studies, testing for tissue-specific gene expression markers predictive of...

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Literature Corpus work: 3c7820f7-b71a-5da3-82f5-2ba07a73bd21
DOI: 10.1101/2022.10.22.513279

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