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CAN-Scan: A multi-omic phenotype-driven precision oncology platform identifies prognostic biomarkers of therapy response for colorectal cancer

1 Apr 2025

Abstract excerpt

Application of machine learning (ML) on cancer-specific pharmacogenomic datasets shows immense promise for identifying predictive response biomarkers to enable personalized treatment. We introduce CAN-Scan, a precision oncology platform, which applies ML on next-generation pharmacogenomic datasets generated from a freeze-viable biobank of patient-derived primary cell lines (PDCs). These PDCs are screened against...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40187357
DOI: 10.1016/j.xcrm.2025.102053

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