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Cross-tissue single-cell transcriptomics reveals organizing principles of fibroblasts in health and disease

2021-01-17

Abstract excerpt

Fibroblasts are non-hematopoietic structural cells that define the architecture of organs, support the homeostasis of tissue-resident cells and play key roles in fibrosis, cancer, autoimmunity and wound healing. Recent studies have described fibroblast heterogeneity within individual tissues. However, the field lacks a definition of fibroblasts at single-cell resolution across tissues in healthy and diseased organ...

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Literature Corpus work
db2fd89d-5103-5b0e-a1c1-72d1edb43a74
DOI
10.1101/2021.01.15.426912
Open publication

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Cross-tissue single-cell transcriptomics reveals organizing principles of fibroblasts in health and diseaseDOI 10.1101/2021.01.15.426912
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