Article

Transcriptomic and Metabolomic Profiling Reveal the p53-Dependent Benzeneacetic Acid Attenuation of Silica-Induced Epithelial–Mesenchymal Transition in Human Bronchial Epithelial Cells

2020-08-11

Abstract excerpt

<h4>Background: </h4> Silica exposure underlies the development of silicosis, one of the most serious occupational hazards worldwide. We aimed to explore the interaction of the silica-induced epithelial–mesenchymal transition (EMT)-related transcripts with the cellular metabolism regulated by p53. <h4>Methods: </h4>: We knocked out p53 using CRISPR/Cas9 in the human bronchial epithelial (HBE) cell line. The transc...

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Literature Corpus work: 3c1517fe-1fb6-533d-abad-fcdebffffe30
DOI: 10.21203/rs.3.rs-54831/v1

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Transcriptomic and Metabolomic Profiling Reveal the p53-Dependent Benzeneacetic Acid Attenuation of Silica-Induced Epithelial–Mesenchymal Transition in Human Bronchial Epithelial CellsDOI 10.21203/rs.3.rs-54831/v1Read

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