scAI-SNP: a method for inferring ancestry from single-cell data

Abstract excerpt

Collaborative efforts, such as the Human Cell Atlas, are rapidly accumulating large amounts of single-cell data. To ensure that single-cell atlases are representative of human genetic diversity, we need to determine the ancestry of the donors from whom single-cell data are generated. Self-reporting of race and ethnicity, although important, can be biased and is not always available for the datasets already collect...

Topics

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• Ethnicity
• Gene Expression Profiling
• Gene Frequency
• Genome, Human
• Polymorphism, Single Nucleotide
• Single-Cell Analysis
• Single-Cell Gene Expression Analysis
• Transcriptome

Identifiers and source

Literature Corpus work

3c131aeb-ed9e-5262-9d6c-7d56ed755ea3

DOI

10.1101/2024.05.14.594208