Article

Reducing INDEL calling errors in whole-genome and exome sequencing data

2014-06-10

Abstract excerpt

<h4>Background</h4> INDELs, especially those disrupting protein-coding regions of the genome, have been strongly associated with human diseases. However, there are still many errors with INDEL variant calling, driven by library preparation, sequencing biases, and algorithm artifacts. <h4>Methods</h4> We characterized whole genome sequencing (WGS), whole exome sequencing (WES), and PCR-free sequencing data from t...

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Literature Corpus work: 519b9763-f17d-5a06-add8-831611c5af64
DOI: 10.1101/006148

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