Article

MFG-E8, A Novel Target of Promoting Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells

2021-09-21

Abstract excerpt

<h4>Background: </h4> Fracture nonunion and bone defects are challenging for orthopedic surgeons. Milk fat globule-epidermal growth factor 8 (MFG-E8), a glycoprotein possibly secreted by macrophages in a fracture hematoma, participates in bone development. However, the role of MFG-E8 in the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) is unclear. <h4>Methods: </h4> We investigated the o...

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Literature Corpus work: 3b9ef62c-1600-589e-bb2c-da3bab79a0e8
DOI: 10.21203/rs.3.rs-892581/v1

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