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Article

Mesenchymal stem cells-derived MFG-E8 accelerates diabetic cutaneous wound healing.

Journal of dermatological science - 1 Jun 2017

Uchiyama Akihiko, Motegi Sei-Ichiro, Sekiguchi Akiko, Fujiwara Chisako, Perera Buddhini, Ogino Sachiko, Yokoyama Yoko, Ishikawa Osamu

Abstract excerpt

BACKGROUND: Diabetic wounds are intractable due to complex factors, such as the inhibition of angiogenesis, dysfunction of phagocytosis by macrophages and abnormal inflammatory responses. It is recognized that mesenchymal stem cells (MSCs) promote wound healing in diabetic mice. We previously demonstrated that MSCs produce large amounts of MFG-E8. OBJECT: The objective was to ascertain the role of MSCs-derived...

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Share to Diabetes Complications
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28302404
DOI: 10.1016/j.jdermsci.2017.02.285

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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