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Comparative secretome analysis of human bone marrow‐derived mesenchymal stem cells during osteogenesis

1 Jun 2012

Abstract excerpt

Osteogenesis is a tightly regulated process that involves coordinated extracellular signals from autocrine and paracrine loops. Secretory proteins during osteogenesis can inhibit cell proliferation and activate cell differentiation toward mature osteoblasts, which are characterized by mineralization. In this study, we attempted to identify these secretory proteins during osteogenesis using LC-MS/MS analysis. We...

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PMID: 22674502
DOI: 10.1002/jcp.24123

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