Article

Integration of gene expression with computational modeling reveals region-specific brain energy metabolism dysregulation in schizophrenia

2025-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Schizophrenia is a highly heritable psychiatric disorder with suggested disturbances in multiple neurobiological pathways including brain energy metabolism, which is essential for sustaining precise neuronal signaling. The relationship between gene expression alterations and energy metabolism defects, however, is poorly understood. Here we combined differential expression (DE) analysis with comp...

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Literature Corpus work: 3b9ef36d-4aaa-5031-a290-c3fa0a73da34
DOI: 10.64898/2025.12.22.695881

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