Article

Connectivity analyses of bioenergetic changes in schizophrenia: Identification of novel treatments

2018-06-05

Abstract excerpt

<h4>ABSTRACT</h4> We utilized a cell-level approach to examine glycolytic pathways in the DLPFC of subjects with schizophrenia (n=16) and control (n=16) subjects and found decreased mRNA expression of glycolytic enzymes in pyramidal neurons, but not astrocytes. To replicate these novel bioenergetic findings, we probed independent datasets for bioenergetic targets and found similar abnormalities. Next, we used a n...

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Literature Corpus work: 068c938b-e174-59b9-a477-c652f1e47268
DOI: 10.1101/338392

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