Article

Integrated analysis of human transcriptome data for Rett syndrome finds a network of involved genes

2018-03-01

Abstract excerpt

Rett syndrome (RTT) is a rare disorder causing severe intellectual and physical disability. The cause is a mutation in the gene coding for the methyl-CpG binding protein 2 (MECP2), a multifunctional regulator protein. Purpose of the study was integration and investigation of multiple gene expression profiles in human cells with impaired MECP2 gene to obtain a data-driven insight in downstream effects. Information...

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Literature Corpus work: 3b421cc5-e15f-5dce-8aa4-2466ab913b3e
DOI: 10.1101/274258

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