Article

A cystic fibrosis lung disease modifier locus harbors tandem repeats associated with gene expression

2022-03-31

Abstract excerpt

Variable number of tandem repeats (VNTRs) are major source of genetic variation in human. However due to their repetitive nature and large size, it is challenging to genotype them by short-read sequencing. Therefore, there is limited understanding of how they contribute to complex traits such as cystic fibrosis (CF) lung function. Genome-wide association study (GWAS) of CF lung disease identified two independent s...

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Literature Corpus work: 3b40b38d-631f-5cd9-8b10-0b0908430850
DOI: 10.1101/2022.03.28.22272580

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