Article

Evolution of local mutation rate and its determinants

2016-05-22

Abstract excerpt

Mutation rate varies along the human genome, and part of this variation is explainable by measurable local properties of the DNA molecule. Moreover, mutation rates differ between orthologous genomic regions of different species, but the drivers of this change are unclear. Here, we compare the local mutation rates of several species. We show that these rates are very similar between human and apes, implying that th...

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Literature Corpus work: 3b11a85f-44a6-50f1-918f-afc4ba28932e
DOI: 10.1101/054825

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