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Single cell transcriptional analysis of human adenoids identifies molecular features of airway microfold cells

26 Jul 2025

Abstract excerpt

The nasal, oropharyngeal, and bronchial mucosa are primary contact points for airborne pathogens like Mycobacterium tuberculosis (Mtb), SARS-CoV-2, and influenza virus. While mucosal surfaces can function as both entry points and barriers to infection, mucosa-associated lymphoid tissues (MALT) facilitate early immune responses to mucosal antigens. MALT contains a variety of specialized epithelial cells, including...

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PMID: 40721095
DOI: 10.1016/j.mucimm.2025.07.006

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