Article

Optoretinography reveals rapid rod photoreceptor movement upon photoisomerization

2025-03-25

Abstract excerpt

Rod photoreceptors are essential for vision under dim light conditions. The onset of rod-mediated vision is marked by the isomerization of rhodopsin. Here we demonstrate that human and rodent rods undergo a minute and rapid contraction of their outer segments immediately upon photoisomerization. The contraction is explained as an electro-mechanical manifestation of the rod early receptor potential generated in the...

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Literature Corpus work: 3ae6f5c5-98bb-5d76-b557-bb914737cdcc
DOI: 10.1101/2025.03.22.644466

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