Article

Cell cycle regulation of the psoriasis associated gene <i>CCHCR1</i> by transcription factor E2F1

2023-04-08

Abstract excerpt

The coiled-coil alpha-helical rod protein 1 (CCHCR1) was first identified as a candidate gene in psoriasis and has lately been associated with COVID-19 susceptibility. Located within P-bodies and centrosomes, its exact cellular role and transcriptional control remain largely unknown. Here, we showed that CCHCR1 shares a bidirectional promoter with its neighboring gene, TCF19 . This bidirectional promoter is acti...

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Literature Corpus work: 3ab2d500-83d0-5bf1-9fe5-f5645e908a56
DOI: 10.1101/2023.04.08.535951

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