Article
Surgical meshes coated with mesenchymal stem cells provide an anti-inflammatory environment by a M2 macrophage polarization.
Acta biomaterialia - 1 Feb 2016
Blázquez Rebeca, Sánchez-Margallo Francisco Miguel, Álvarez Verónica, Usón Alejandra, Casado Javier G
Abstract excerpt
Surgical meshes are widely used in clinics to reinforce soft tissue's defects, and to give support to prolapsed organs. However, the implantation of surgical meshes is commonly related with an inflammatory response being difficult to eradicate without removing the mesh. Here we hypothesize that the combined use of surgical meshes and mesenchymal stem cells (MSCs) could be a useful tool to reduce the inflammatory...
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