Back to search

Article

Metabolic Connectivity Gradients of the Human Brain

2026-01-29

Abstract excerpt

The functional architecture of the brain is organised along continuous, macro-scale gradients. However, it is unknown if the metabolic architecture of the brain displays similar gradient characteristics. Here, we use functional positron emission tomography (fPET) with 18F-fluorodeoxyglucose (FDG) to characterise the metabolic connectivity gradients of the brain and determine how neurobiological mechanisms shape th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3a802f23-1b0d-597b-8122-46e70b8b6553
DOI
10.64898/2026.01.28.702441
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Metabolic Connectivity Gradients of the Human BrainDOI 10.64898/2026.01.28.702441
Metabolism-weighted brain connectome reveals synaptic integration and vulnerability to neurodegenerationSemantic proximity
Metabolic connectivitySemantic proximity
Energetic implications of fMRI-based nodal complex network metrics: a complex picture unfolds across diverse brain statesSemantic proximity
Mapping energy metabolism systems in the human brainSemantic proximity
Neuro-Vascular-Metabolic Dysregulation, Metabolic Connectomics, and Metabolic Functional Changes in Alzheimer’s Disease: A Preclinical and Clinical ComparisonSemantic proximity
Unveiling functional-metabolic synergy in the healthy brain: multivariate integration of dynamic [ <sup>18</sup> F]FDG-PET and resting-state fMRISemantic proximity
Large-scale reorganization of cortical hierarchy, dynamics, and information processing in subjective cognitive declineSemantic proximity
Meta analysis of glucose metabolism across Alzheimer’s, Parkinson’s and ALS Reveals emergence of adaptive brain glucometabolic responses and associated neurological functional profilesSemantic proximity
Disrupted dynamics of brain structure–function coupling link genetic risk of Alzheimer’s Disease and aging to cognitive decline in 34,067 adultsSemantic proximity
Connections across regional glymphatic clearance, neural activity and amyloid-β deposition in cortexSemantic proximity
Constructing the Human Brain Metabolic Connectome Using MR Spectroscopic Imaging: Insights into Biochemical Organization, Cytoarchitectonic Similarity and Gene Co-expression NetworksSemantic proximity
Multiscale Metabolic Covariance Networks Uncover Stage-Specific Biomarker Signatures Across the Alzheimer’s Disease ContinuumSemantic proximity
Select a neighboring publication to make it the new centre.