Article

Unveiling ESR1's Network Centrality Through Multi-Omics Fusion and AI: Implications for Next-Generation Endocrine Therapies

2025-10-08

Abstract excerpt

Estrogen Receptor 1 (ESR1) remains a cornerstone therapeutic target in estrogen receptor-positive (ER+) breast cancer, driving ~70% of cases through dysregulated endocrine signalling. This study leverages the Swalife PromptStudio platform, an AI-native framework integrating large language models for structured target deconvolution, to generate a comprehensive multi-dimensional profile of ESR1. Through literature m...

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Literature Corpus work: 3a665bac-190e-5fe6-9aad-38e020f998c3
DOI: 10.20944/preprints202510.0629.v1

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