Article

A framework for automated multimodal HDX-MS analysis

2025-03-15

Abstract excerpt

<h4>ABSTRACT</h4> We present pyHXExpress, a customizable codebase for automated high-throughput multimodal analysis of all spectra generated from HDX-MS experiments. The workflow was validated against a synthetic test dataset to test the fitting algorithms and to confirm the statistical outputs. We further establish a framework for the determination of multimodality throughout a protein system by rigorous evaluat...

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Literature Corpus work: 39e4f02d-1d64-5611-b2e1-f52762a50980
DOI: 10.1101/2025.03.13.643099

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