Article
The SysteMHC Atlas project.
Nucleic acids research - 4 Jan 2018
Shao Wenguang, Pedrioli Patrick G A, Wolski Witold, Scurtescu Cristian, Schmid Emanuel, Vizcaíno Juan A, Courcelles Mathieu, Schuster Heiko, Kowalewski Daniel, Marino Fabio, Arlehamn Cecilia S L, Vaughan Kerrie, Peters Bjoern, Sette Alessandro, Ottenhoff Tom H M, Meijgaarden Krista E, Nieuwenhuizen Natalie, Kaufmann Stefan H E, Schlapbach Ralph, Castle John C, Nesvizhskii Alexey I, Nielsen Morten, Deutsch Eric W, Campbell David S, Moritz Robert L, Zubarev Roman A, Ytterberg Anders Jimmy, Purcell Anthony W, Marcilla Miguel, Paradela Alberto, Wang Qi, Costello Catherine E, Ternette Nicola, van Veelen Peter A, van Els Cécile A C M, Heck Albert J R, de Souza Gustavo A, Sollid Ludvig M, Admon Arie, Stevanovic Stefan, Rammensee Hans-Georg, Thibault Pierre, Perreault Claude, Bassani-Sternberg Michal, Aebersold Ruedi, Caron Etienne
Abstract excerpt
Mass spectrometry (MS)-based immunopeptidomics investigates the repertoire of peptides presented at the cell surface by major histocompatibility complex (MHC) molecules. The broad clinical relevance of MHC-associated peptides, e.g. in precision medicine, provides a strong rationale for the large-scale generation of immunopeptidomic datasets and recent developments in MS-based peptide analysis technologies now...
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