Article

Phase variable glycosylation in non-typeable <i>Haemophilus influenzae</i>

2019-08-22

Abstract excerpt

Non-typeable Haemophilus influenzae (NTHi) is a leading cause of respiratory tract infections worldwide and continues to be a global health burden. Adhesion and colonisation of host cells are crucial steps in bacterial pathogenesis, and in many strains of NTHi interaction with the host is mediated by the high molecular weight adhesins HMW1A and HMW2A. These adhesins are N -glycoproteins which are modified by cyt...

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Literature Corpus work: 39e40e8f-8646-5171-8be6-2f040f335bdc
DOI: 10.1101/744037

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