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Article

Deciphering Steroid Receptor Crosstalk in Hormone-Driven Cancers

10 Oct 2018

Abstract excerpt

Steroid hormone receptors (SRs) have a multitude of functions in human biology and disease progression. The SR family of related ligand-activated transcription factors includes androgen, estrogen, glucocorticoid, mineralocorticoid, and progesterone receptors. Antiestrogen or estrogen receptor (ER)-targeted therapies to block ER action remain the primary treatment of luminal breast cancers. Although this strategy...

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PMID: 30307542
DOI: 10.1210/en.2018-00831

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