Article

Inflammasome Profiling in Human Natural Killer Cells under Pro-inflammatory Stimuli and Solid Organ Transplantation

2024-04-19

Abstract excerpt

<h4>Summary</h4> Innate immunity relies on inflammasomes as key mediators of host defense, orchestrating the release of pro-inflammatory cytokines and triggering pyroptotic cell death in response to harmful stimuli. Although inflammasome activity has been extensively studied in myeloid cells, its role in natural killer (NK) cells remains underexplored. This study demonstrates that human primary NK cells can funct...

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Literature Corpus work: 393ee257-ab4d-55cb-a052-419d41de1708
DOI: 10.1101/2024.04.17.589865

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