Article
Machine Learning Identifies Novel Candidates for Drug Repurposing in Alzheimer’s Disease
2020-05-16
Abstract excerpt
Clinical trials of novel therapeutics for Alzheimer’s Disease (AD) have consumed a large amount of time and resources with largely negative results. Repurposing drugs already approved by the Food and Drug Administration (FDA) for another indication is a more rapid and less expensive option. Repurposing can yield a useful therapeutic and also accelerate proof of concept studies that ultimately lead to a new molecul...
Topics
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- Alzheimer's disease research and treatments
- Amyotrophic Lateral Sclerosis Research
- Bioinformatics and Genomic Networks
- Cholinesterase and Neurodegenerative Diseases
- Computational Drug Discovery Methods
- Neuroinflammation and Neurodegeneration Mechanisms
- Pluripotent Stem Cells Research
- Protein Degradation and Inhibitors
Identifiers and source
- Literature Corpus work
- c821cc97-4051-5d3b-a895-f617d0f88c11
- DOI
- 10.1101/2020.05.15.098749
