Article

A Semi-Automated MEA Spike sorting (SAMS) method for high throughput assessment of cultured neurons

2025-02-09

Abstract excerpt

Neurons derived from human pluripotent stem cells (hPSCs) are valuable models for studying brain development and developing therapies for brain disorders. Evaluating human-derived neurons requires assessing their electrical activity, which can be achieved using multi-electrode arrays (MEAs) for extracellular recordings. Because each electrode channel generally detects activity from multiple neurons, resolving the...

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Literature Corpus work: 39286cd6-9d3f-5566-8af0-03f10c878044
DOI: 10.1101/2025.02.08.637245

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