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Mitochondrial dysfunction and potential anticancer therapy

6 Jul 2017

Abstract excerpt

Mitochondrial dysfunction (MDF) has been identified as an important factor in various diseases ranging from neurological disorders, to diseases of the cardiovascular system and metabolic syndromes. MDF was also found in cancer as well as in cancer predisposition syndromes with defective DNA damage response (DDR) machinery. Moreover, a recent highlight arises from the detection of MDF in eukaryotic cells upon...

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PMID: 28682452
DOI: 10.1002/med.21459

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