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Article

Impact of single nucleotide polymorphisms on tacrolimus pharmacokinetics in liver transplant patients after switching to once-daily dosing

2022-04-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: The effects of multidrug resistance-1 (<italic>MDR1</italic>), <italic>ABCC2</italic>, and P450 oxidoreductase (POR)*28 gene polymorphisms on tacrolimus metabolism following a switch to once-daily dosing have not been elucidated. We investigated the effects of recipient and donor <italic>CYP3A5</italic>,<italic> MDR1</italic>,<italic> ABCC2</italic>, and <italic...

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Literature Corpus work
386c9c81-f4f6-5bdd-93ea-68fdf5565f79
DOI
10.21203/rs.3.rs-1553480/v1
Open publication

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Impact of single nucleotide polymorphisms on tacrolimus pharmacokinetics in liver transplant patients after switching to once-daily dosingDOI 10.21203/rs.3.rs-1553480/v1
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