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Frequency of occurrence and types of mutations in the rpoB, katG, inhA, and ahpC genes associated with rifampicin and isoniasid resistance in M. tuberculosis strains circulating in the Kyrgyz Republic

2008-12-01

Abstract excerpt

The availability of an MDR TB-Biochip for the express detection of Mycobacterium tuberculosis (MBT) strains resistant to rifampicin and isoniasid has been studied in 940 patients with pulmonary tuberculosis. The rpoB gene of rifampicin-resistant MBT strains circulating in the Kyrgyz Republic was shown to have substitutions at codons 531, 526, 516, 511, 513, 512, 533, and 522. MBT strains with mutations at codons 5...

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Literature Corpus work
38619154-8cf0-50e3-b46d-cb25fbe5b162
DOI
10.3103/s0891416808040083
Open publication

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Frequency of occurrence and types of mutations in the rpoB, katG, inhA, and ahpC genes associated with rifampicin and isoniasid resistance in M. tuberculosis strains circulating in the Kyrgyz RepublicDOI 10.3103/s0891416808040083
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