Article
Molecular characteristics of rifampicin- and isoniazid-resistant Mycobacterium tuberculosis isolates from the Russian Federation.
The Journal of antimicrobial chemotherapy - 1 Jun 2007
Afanas'ev Maxim V, Ikryannikova Larisa N, Il'ina Elena N, Sidorenko Sergey V, Kuz'min Aleksey V, Larionova Elena E, Smirnova Tat'yana G, Chernousova Larisa N, Kamaev Eugeny Yu, Skorniakov Sergey N, Kinsht Vladimir N, Cherednichenko Andrey G, Govorun Vadim M
Abstract excerpt
OBJECTIVES: Three Mycobacterium tuberculosis genetic loci--rpoB and katG genes and the fabG1(mabA)-inhA operon promoter region--were studied to reveal the mutations associated with rifampicin and isoniazid resistance. METHODS: Four hundred and twelve isolates of M. tuberculosis from different regions of the Russian Federation were collected during 1997-2005. A matrix-assisted laser-desorption...
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