Article
[Distribution of mutations in the rpoB, katG, inhA, ahpC gene of rifampicin and isoniazid resistant M. tuberculosis strains isolated in Kyrgyz Republic].
Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Jan 2008
Isakova Zh T
Abstract excerpt
The aim of this work was to evaluate the prevalence mutations in the rpoB, katG, inhA, ahpC gene of rifampicin and isoniazid resistant M. tuberculosis (Tb) isolates from Kyrgyz Republic using OA Biochip MDR. In the rifampicin-resistant strains, the mutations were identified in the codons 531, 526, 516, 511, 513, 512, 533, and 522. The most prevalent point mutations were Ser531RLeu at the codon 531 (59.7%)....
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