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Differential Binding of ΔFN3 Proteins of <em>Bifidobacterium longum</em> GT15 and <em>Bifidobacterium bifidum</em> 791 to Cytokines Determined by Surface Plasmon Resonance and <em>de Novo</em> Molecular Modeling

2025-09-26

Abstract excerpt

Bifidobacteria, a genus of obligate anaerobes, comprise a major component of the intestinal microbiota. Importantly, bifidobacteria participate in the immune reactions. These bacteria carry a species-specific operon in which the fn3 gene encodes a multifunctional protein FN3 that mediates the bacterial adhesion to the intestinal epithelium and is capable of binding individual cytokines. Bioinformatics and biochemi...

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Literature Corpus work
384b91ef-15a3-58a7-8857-99f2ca032e4f
DOI
10.20944/preprints202509.2197.v1
Open publication

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Differential Binding of ΔFN3 Proteins of <em>Bifidobacterium longum</em> GT15 and <em>Bifidobacterium bifidum</em> 791 to Cytokines Determined by Surface Plasmon Resonance and <em>de Novo</em> Molecular ModelingDOI 10.20944/preprints202509.2197.v1
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