Article
The importance of vaccinated individuals to population-level evolution of pathogens
2022-11-29
Abstract excerpt
Virus evolution shapes the epidemiological patterns of infectious disease, particularly via evasion of population immunity. At the individual level, host immunity itself may drive viral evolution towards antigenic escape. Using compartmental SIR-style models with imperfect vaccination, we allow the probability of immune escape to differ in vaccinated and unvaccinated hosts. As the relative contribution to selectio...
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Identifiers and source
- Literature Corpus work
- 382e6ed4-27c4-5fd1-9c87-524ffd357b9f
- DOI
- 10.1101/2022.11.29.22282822