Article
Inflammatory Molecular Networks in Age-Related Meniscus Injury: TLR/NF-κB Signaling, Immune Dysregulation, and Epigenetic Modifications
2025-06-25
Abstract excerpt
<title>Abstract</title> <p> Background: The meniscus plays a crucial biomechanical role in the knee joint, and its injury often leads to degenerative joint diseases. Aging significantly increases the risk of meniscus injury, with emerging evidence suggesting dysregulated inflammatory responses as a key factor. This study investigated the inflammatory molecular mechanisms underlying age-related meniscus injury a...
Topics
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- Connective Tissue Growth Factor Research
- Cytokine Signaling Pathways and Interactions
- interferon and immune responses
- Knee injuries and reconstruction techniques
- Mast cells and histamine
- Osteoarthritis Treatment and Mechanisms
- Rheumatoid Arthritis Research and Therapies
- Spine and Intervertebral Disc Pathology
Identifiers and source
- Literature Corpus work
- 37fe9dda-3145-5c75-a272-0f2f4b69907f
- DOI
- 10.21203/rs.3.rs-6559896/v1
