Article

Identification And Validation of Pivotal Genes Related To Meniscus Senescence Based On Gene Expression Profiling Analysis And In Vivo And In Vitro Models Detection

2021-06-25

Abstract excerpt

<h4>Background: </h4> The compositional change in the meniscus with aging would increase the tissue vulnerability of the meniscus, which would induce meniscus tearing. Here, we investigated the molecular mechanism of age-related meniscus degeneration with gene expression profiling analysis, and validate pivotal genes in vivo and in vitro models. <h4>Methods: </h4>: The GSE45233 dataset, including 6 elderly meniscu...

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Literature Corpus work: 19174751-cee5-5143-ad02-46b713976925
DOI: 10.21203/rs.3.rs-601815/v1

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