Article

Age-associated reduction of nuclear shape dynamics in excitatory neurons of the visual cortex

2022-08-22

Abstract excerpt

Neurons decline in their functionality over time, and age-related neuronal alterations are associated with phenotypes of neurodegenerative diseases. In non-neural tissues, an infolded nuclear shape has been proposed as a hallmark of aged cells and neurons with infolded nuclei have also been reported to be associated with neuronal activity. Here, we perform time-lapse imaging in the visual cortex of Nex-Cre;SUN1-G...

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Literature Corpus work: 37ad515c-c540-5d7e-ad6f-ae1f0d56bf66
DOI: 10.1101/2022.08.22.504704

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