Article

3d virtual histology reveals pathological alterations of cerebellar granule cells in multiple sclerosis

2022-10-10

Abstract excerpt

We investigate structural properties of neurons in the granular layer of human cerebellum with respect to their involvement in multiple sclerosis (MS). To this end we analyze data recorded by X-ray phase contrast tomography from tissue samples collected post mortem from a MS and a healthy control group. Using automated segmentation and histogram analysis based on optimal transport theory (OT) we find that the dist...

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Identifiers and source

Literature Corpus work: f79a12af-a636-543c-bacf-51955ef2f24b
DOI: 10.1101/2022.10.07.22280811

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