Article

Functional Characterisation of Engineered Bacterial Biosensors for Kynurenine Detection

2025-04-04

Abstract excerpt

The kynurenine (KYN) pathway is the major catabolic pathway for tryptophan in humans, producing several metabolites that influence health. In clinical settings, KYN levels serve as a valuable biomarker for diagnosis and prognosis of inflammatory and neurological diseases. Nevertheless, KYN detection relies on mass spectrometry analysis, which requires specialised knowledge and expertise with high operational costs...

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Literature Corpus work: 37a649cb-3149-58d6-a980-55a0cae6df2e
DOI: 10.1099/acmi.0.001031.v1

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