Article

Development of DNA-encoded cell-free biosensors for the detection of bacterial infections

2017-01-01

Abstract excerpt

This thesis describes the development of cell-free biosensors for the detection of quorum- sensing molecules in human clinical samples. The biosensor devices were comprised of a transcription factor and a regulated GFP reporter output that was expressed in the presence of the target molecule. The genetic circuit was encoded on a DNA plasmid and expressed in a cell-free system, consisting of the basic transcription...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6eaed668-d288-578c-b3b5-b02e4b159303
DOI: 10.25560/58206

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Development of DNA-encoded cell-free biosensors for the detection of bacterial infectionsDOI 10.25560/58206Read

Detection of Quorum-Sensing Molecules for Pathogenic Molecules Using Cell-Based and Cell-Free BiosensorsSemantic proximity Read

A discovery platform to identify inducible synthetic circuitry from varied microbial sourcesSemantic proximity Read

Engineered Bacteria for Short-Chain-Fatty-Acid-Repressed Expression of Biotherapeutic MoleculesSemantic proximity Read

Implementation of Probiotic Bacteria for Monitoring Intestinal InflammationSemantic proximity Read

Semi-automated Production of Cell-free BiosensorsSemantic proximity Read

Monitoring intracellular antibiotic concentrations in real-time using allosteric biosensorsSemantic proximity Read

Custom-Made Quorum Sensing for a Eukaryote.Semantic proximity Read

Design of a transcriptional biosensor for the portable, on-demand detection of cyanuric acidSemantic proximity Read

Surveying the Genetic Design Space for Transcription Factor-Based Metabolite Biosensors: Synthetic Gamma-Aminobutyric Acid and Propionate Biosensors in E. coli Nissle 1917Semantic proximity Read

In-Situ Monitoring of Xenobiotics using Genetically Engineered Whole-Cell-Based Microbial Biosensors: Recent Advances and OutlookSemantic proximity Read

Engineering Coupled Consortia-Based Biosensors using Incoherent Feedforward LoopsSemantic proximity Read

N-Acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilmsSemantic proximity Read