Mathematical modeling links benefits of short and long antibiotic treatment to details of infection

Abstract excerpt

Antibiotics are the major tool for treating bacterial infections. With rising antibiotic resistance in microbes, strategies that limit further evolution and spread of drug resistance are urgently needed, in individuals and populations. While classical recommendations favor longer and aggressive treatments, more recent studies and clinical trials advocate for moderate regimens. In this debate, two axes of aggressiv...

Topics

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• Anti-Bacterial Agents
• Bacterial Infections
• Computer Simulation
• Drug Administration Schedule
• Drug Resistance, Bacterial
• Drug Therapy, Combination
• Microbial Sensitivity Tests
• Models, Biological

Identifiers and source

Literature Corpus work

3790c8f8-6c59-5d34-83b2-41f0806199da

DOI

10.1101/555334