Article

A generic technology for long-acting intravitreal therapy

2026-01-21

Abstract excerpt

<title>Abstract</title> <p>Intravitreal (IVT) injection is a crucial drug delivery method for ocular diseases, but it requires frequent administration due to short drug half-lives. This study presents a novel approach to long-acting IVT therapy using biodegradable tetra-PEG hydrogel microspheres (MSs) as drug carriers. These MSs, approximately 50 μm in diameter, are designed with β-eliminative cleavable linkers t...

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Literature Corpus work: 378c2186-e024-5f9c-98eb-1618d1d7fb7d
DOI: 10.21203/rs.3.rs-8408708/v1

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